Introducing ZEPHYRx

It's amazing what a few deep breaths can do.

The ZEPHYRx™ platform combines incentive spirometry with an engaging selection of breath-driven video games, encouraging more frequent usage, and better patient outcomes.

Better Breathing Can Lead to Healthier Patients

Fun, diverse breathing games keep patients engaged. Patients control the game play with their breath, following on screen prompts to inhale/hold/exhale via the bluetooth connected spirometer. This elicits greater participation and patient adherence to their prescribed respiratory therapy.


ZEPHYRx Features

World-Class Design

ZEPHYRx features over 15 breath-powered games, including golf, slot machines, car racing, and fishing. There's something for everyone. And we use a fully FDA & CE medically cleared device for all game play.

Adapts to your breath capacity

Our games automatically adapt to your current breath capacity. We adjust the difficulty level based on your game play results.

Multi-Platform Compatibility

ZEPHYRx works on mobile phones (Apple iPhone & Android) as well as tablets (Apple iPad and Android). Download them from the Apple App Store or Google Play Store!

Results sent to your healthcare team

With your consent we save and transmit the results of your breathing exercises to your electronic health record (EHR) for review by your entire health care team.

Video games increase pain tolerance

As shown in multiple studies, video games increase pain tolerance through active distraction which in turns increases game plan duration.
(Jameson, Trevena, and Swain, Electronic
gaming as pain distraction, 2011)

Large clinical trial

Our games are tested within a large NIH-sponsored clinical trial with over 300 patients focusing on post-operative surgery recovery and children with cystic fibrosis

MULTI-PLATFORM / Breath-powered



Breath-driven games


NIH-sponsored Clinical Trials


Results delivered to EHR


Patient Clinical Trial

ZEPHYRx Quick Facts

Our NIH-sponsored clinical trial investigates the efficacy of video games for respiratory therapy in reducing post-surgery atelectasis, which can be a leading indicator of hospital-acquired pneumonia.


Executive Leadership

Dwight Cheu
Silicon Valley exec (7 positive exits) with successful market introductions of Oracle v6 database, Tony Hawk & Spiderman on mobile, & big-data analytics.
Michael DiCesare
Principal Investigator on our clinical trials. Proven sales professional. Holder of multiple patents and trademarks.
Sue Whalen
Committed successful operations executive, primary ZEPHYRx investor and majority owner. Has grown her business from $0 to $500M.

Advisory Board

Robert Barry
Medical Device Startup Entrepreneur
Robert has over 30 years of experience in all facets of medical device companies including founding medical device companies, securing funding for medical device companies as CEO and inventing novel solutions used to start and build value in companies as CTO.
Frank DeBernardis
Founder & Operating Partner, Gore Range Capital
Frank has more than 40 years of medical therapeutic and diagnostic device experience with deep relationships and expertise in cardiovascular, orthopedic, aesthetics, and wound care. He served as National Sales Manager for Medtronic, Inc., where he converted the Medtronic distributor network to a fully integrated direct salesforce.
Rachael Hagan
President & CEO, NephroDI Therapeutics
Rachael is a recognized leader with a demonstrated track record of commercializing early-stage technology out of universities. Ms. Hagan is experienced in promoting emerging technologies and businesses to investors with a strong track record of identifying, planning, and implementing strategic partnerships.
Robert Newman
Rob Newman, MS, MBA, RAC has over 35 years’ experience in the medical device arena. He has held roles in Engineering, Regulatory Affairs, Clinical Affairs and Quality. Most recently he was the Sr. Director for Regulatory Affairs at Johnson & Johnson Diabetes Care.


43 New Scotland Ave
Albany, NY 12208

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(888) 452-6269

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